Liver atoll sign: Nodular regenerative hyperplasia

Nodular regenerative hyperplasia of the liver.

Nodular regenerative hyperplasia (NRH), characterized by diffuse hepatic micronodular transformation in groups without fibrous septa between the nodules, is a rare benign liver lesion that has many synonyms in previous literature. Pathologic evaluation is the mainstay of accurate diagnosis. Treatment is focused on its underlying conditions and complications of portal hypertension. A 39-year-old...

Nodular regenerative hyperplasia

Nodular Regenerative Hyperplasia

Introduction: Nodular regenerative hyperplasia (NRH) is a known etiology of noncirrhotic portal hypertension. Cases of biopsy-proven NRH in human immunodeficiency virus (HIV)–positive patients have been described. While these patients often have normal synthetic liver function, several reports described disease progression to liver failure. Case: We here present a 26-year-old woman with history...

Liver nodular regenerative hyperplasia after bone marrow transplant.

237-40. 4. Hunt DM, Higgs DR, Winichagoon P, Clegg JB, Weatherall DJ. Haemoglobin Cs Sp has an unstable α chain messenger RNA. Br J Haematol 1982; 51:40513. 5. Harteveld CL, Traeger-Synodinos J, Ragusa A, et al. Multicentric origin of Hb Constant Spring [α2 codon 142 TAA-CAA]. Br J Haematol 1998; 102:50. 6. Pootrakul P, Winichagoon P, Fucharoen S, Pravatmuang P, Piankijagum A, Wasi P. Homozygou...

Thorotrast associated nodular regenerative hyperplasia of the liver.

A case of nodular regenerative hyperplasia (NRH) of the liver is described in association with exposure to the radiographic contrast medium Thorotrast. This is the first case in which the pathological findings have been fully documented. It is suggested that NRH may have developed through Thorotrast induced damage to portal vein radicles.